Table 1.
Genotype–phenotype correlation: univariable comparison of statistically significant parameters. Patients with BBS1 vs BBS10. Only statistically significant results are included. The full analysis is available in Tables S1, Supporting information
| BBS 1 |
BBS 10 |
||||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | p-Valuea | |
| Anthropomorphic measurements | |||||
| Age at clinic | 30.5 | −15.48 | 22.32 | −8.95 | 0.034 |
| Height (cm) | 163.92 | −28.17 | 162.93 | −9.31 | 0.031 |
| Inflammatory markers | |||||
| CRP (mg/l) | 5.69 | −2.74 | 9.53 | −7.12 | 0.04 |
| Endocrine profile | |||||
| C peptide (ng/ml) | 1295.88 | −740.13 | 2333.3 | −1501.27 | 0.014 |
| Lipid profile | |||||
| Triglycerides (mmol/l) | 1.5 | −0.73 | 1.98 | −0.94 | 0.049 |
| Renal profile | |||||
| Potassium (mmol/l) | 4.16 | −0.48 | 4.38 | −0.42 | 0.015 |
| Albumin/creatinine ratio | 7.1 | −22.39 | 5.3 | −11.23 | 0.032 |
ANOVA, analysis of variance; BBS, Bardet–Biedl syndrome, CRP, C-reactive protein.
a
p-Value obtained from anova test or Mann–Whitney U test.