Table 3.
Multivariate Cox regression analysis of factors associated with overall survival
| Multivariate survival (N = 128 patients) | Comparison | Hazard ratio (95% CI) | P |
|---|---|---|---|
| Ascites at baseline | No ascites | 2.21 (1.10, 4.47) | 0.027 |
| Albumin | Unit = 1 g/dl | 0.37 (0.22, 0.64) | <0.001 |
| BCLC Stage C or D | BCLC Stage B | 4.11 (2.11, 8.01) | <0.001 |
| Largest lesion size > 5 cm (including diffuse) | Largest lesion Size < 5 cm | 2.48 (1.31, 4.67) | 0.005 |
| TACE/DEB | Y90 alone | 0.66 (0.37, 1.17) | 0.115 |
| Y90 and TACE/DEB | Y90 alone | 1.09 (0.44, 2.66) | 0.859 |
| Number of treatments | Unit = 1 treatment | 0.73 (0.52, 1.04) | 0.079 |
| Progressive disease | Complete Response | 7.62 (2.21, 26.3) | <0.001 |
| Stable disease | Complete Response | 5.33 (1.42, 20.0) | 0.013 |
| Partial response | Complete Response | 3.66 (1.01, 13.3) | 0.048 |
The bold text indicates a significant value.
BCLC, Barcelona Clinic Liver Cancer; TACE/DEB, transarterial chemotherapy with drug-eluting beads.