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Effects of miR-221 and miR-222 on growth differ strikingly between lung cancer cell lines. Liquid colony formation assay (A) and WST-1 colorimetric proliferation assay (B) for six lung cancer cell lines and HBEC4 transfected with miR-221 or miR-222 mimics. The results are averages of three independent experiments done in triplicate wells (liquid colony assay) and octuplicate wells (WST-1 assay). *, and *** indicate P < 0.05, and P < 0.001 (Mann–Whitney U test), respectively.
