Table 2.
Dice indices between individual and benchmark modules in patients and controls
Dice index | Group difference | ||||
---|---|---|---|---|---|
Benchmark module | M controls (SD) | M patients (SD) | B [95% CI] | t | P-value |
Functional network | |||||
aDMN+ | 0.613 (0.0703) | 0.607 (0.114) | −0.203 [−1.200 to 0.709] | −0.407 | 0.685 |
pDMN+ | 0.450 (0.143) | 0.252 (0.0613) | 2.023 [1.393 to 2.653] | 6.413 | <0.001* |
SMM | 0.642 (0.116) | 0.569 (0.135) | 0.250 [−0.566 to 1.066] | 0.612 | 0.543 |
POM | 0.595 (0.117) | 0.660 (0.117) | −0.859 [−1.58 to −0.138] | −2.379 | 0.020 |
Anatomical network | |||||
Right lateral motor | 0.273 (0.175) | 0.182 (0.146) | 0.781 [0.196 to 1.366] | 2.665 | 0.010 |
Medial motor | 0.288 (0.169) | 0.215 (0.136) | 0.445 [−0.192 to 1.081] | 1.395 | 0.168 |
Left lateral motor | 0.295 (0.136) | 0.241 (0.169) | 0.125 [−0.506 to 0.757] | 0.396 | 0.694 |
SMA | 0.285 (0.189) | 0.223 (0.117) | 0.441 [−0.214 to 1.096] | 1.344 | 0.183 |
Left occipital | 0.293 (0.212) | 0.242 (0.173) | 0.231 [−0.282 to 0.744] | 0.900 | 0.371 |
Right parietal | 0.347 (0.233) | 0.218 (0.145) | 0.664 [0.167 to 1.162] | 2.668 | 0.010 |
Right occipital | 0.327 (0.278) | 0.253 (0.183) | 0.377 [−0.055 to 0.810] | 1.743 | 0.086 |
Right frontal | 0.201 (0.184) | 0.221 (0.149) | −0.002 [−0.610 to 0.606] | 0.007 | 0.995 |
Left frontal | 0.312 (0.231) | 0.189 (0.144) | 0.621 [0.117 to 1.125] | 2.460 | 0.017 |
All regression models corrected for motion, age, sex, and hippocampal volumes. aDMN+/pDMN+, anterior/posterior default mode network; SMM, sensorimotor network module; POM, parieto-occipital module; SMA, supplementary motor area.
P < 0.05 (after FDR correction).