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. 2015 Mar 12;2(4):401–416. doi: 10.1002/acn3.183

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© 2015 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Methyl supplementation increased theta and alpha rhythm power. (a) Power spectrum density surrounding interictal spikes. (b) Methyl supplementation significantly increased theta rhythm power (F_2,5 = 12.30, P < 0.01, n = 6, one-way analysis of variance [ANOVA] with post hoc test, *significance relative to pre-Met). (c) Methyl supplementation significantly increased alpha rhythm power on day 2 post-Met treatment (F_2,5 = 5.90, P < 0.05, n = 6, one-way ANOVA with post hoc test, *significance relative to pre-Met). Error bars are SEM.