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. 2015 Apr 5;2015:187346. doi: 10.1155/2015/187346

Table 3.

DNA damage according to the comet assay for the assessment of the genotoxicity of J. regia and C. odorata.

Treatments Comet class
Total 0 1 2 3
Blood samples (4 h)
Negative control 40.5 ± 21.41a 77.0 ± 9.38a 10.7 ± 4.08a 7.2 ± 5.60a 5.2 ± 3.54a
CPA (50 mg/kg) 170.2 ± 12.31b 5.0 ± 2.28b 39.0 ± 7.01b 36.8 ± 5.52b 19.2 ± 3.12b
J. regia (100 mg/kg) 64.0 ± 52.44c 60.8 ± 25.4a 20.8 ± 6.83bc 12.0 ± 11.22c 6.4 ± 8.29a
C. odorata (100 mg/kg) 31.8 ± 8.93a 73.3 ± 6.56a 19.8 ± 3.86bc 5.5 ± 5.24a 0.3 ± 0.18c
J. regia (200 mg/kg) 58.7 ± 20.83a 65.5 ± 8.07a 15.5 ± 5.00a 13.8 ± 9.97c 5.2 ± 3.60a
C. odorata (200 mg/kg) 109.5 ± 30.48b 39.2 ± 10.94c 25.7 ± 4.67c 21.7 ± 3.26d 13.5 ± 9.28b
Blood samples (24 h)
Negative control 15.0 ± 3.79a 87.8 ± 3.37a 9.8 ± 3.54a 1.8 ± 0.75a 0.5 ± 0.83a
CPA (50 mg/kg) 96.8 ± 8.93b 29.5 ± 5.08b 47.3 ± 7.14c 20.0 ± 4.56b 3.2 ± 1.94b
J. regia (100 mg/kg) 9.4 ± 7.53a 90.8 ± 7.25a 8.6 ± 6.54a 0.4 ± 0.89a 0a
C. odorata (100 mg/kg) 12.3 ± 4.17a 88.8 ± 3.43a 10.0 ± 2.96a 1.2 ± 1.16a 0a
J. regia (200 mg/kg) 11.8 ± 4.40a 89.2 ± 3.86a 9.8 ± 3.48a 1.0 ± 0.89a 0a
C. odorata (200 mg/kg) 29.3 ± 15.88c 74.7 ± 11.96c 21.2 ± 8.95b 3.8 ± 0.86c 0.2 ± 0.40a

Mean ± standard error. Different letters between groups in each column correspond to significant differences at 4 and 24 hours. P < 0.5, one-way ANOVA; Fisher LSD, comparing the treatments separately at 4 and 24 hours.