Extended Data Figure 8. mTORC1 signaling influences proteasome subunit expression in vivo.

a, Some individual proteasome subunits are shown in the same brain lysates obtained in Fig. 4a. b, Expression of transcripts from representative PSM genes in the livers of the mice described in Fig. 4d,e were measured by qRT-PCR and are presented as mean ± s.e.m relative to fasted controls. (n=4). *p < 0.05 compared to fasted mice, #p < 0.05 compared to refed, vehicle-treated mice. Statistical significance for pairwise comparisons evaluated with a two-tailed Student’s t test.