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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Inflamm Bowel Dis. 2015 May;21(5):996–1005. doi: 10.1097/MIB.0000000000000339

Figure 5.

Figure 5

Real-time PCR for miR-4284 and CXCL5 mRNA levels in colonic tissues from two mouse models of experimental colitis. (A–B) Chronic colitis DSS-induced mouse model. Wild type, C57BL/6J, mice were kept on 3% DSS-containing water ad libitum (DSS, n = 7), for 3 cycles of 5 days, interrupted by 16 days of regular water, as described in the methods section. Mice kept on regular water served as controls (n = 7). (C–D) IL10-deficient mice (IL10-KO, n = 7) and wild-type controls (WT, n = 7) were fed piroxicam-containing diet for 2 weeks, followed by 2 weeks of regular chow. Colonic tissues were collected and RNA was extracted. Data are presented as boxes with whiskers, from minimum to maximum. *p < 0.05, **p < 0.01, t-test, Prism6 (GraphPad Software Inc.).