Table 2.
ID | R | 53BP1 | CBX7 | JARID1A | PHF1 | PHF19 | PHF23 | UHRF1 | L3MBTL1 | L3MBTL3 | MBTD1 |
---|---|---|---|---|---|---|---|---|---|---|---|
7 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | |
8 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | |
9 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | |
10 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | |
11 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | |
12 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | |
13 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 |
IC50 values are the average of at least 3 values ± the standard deviation as determined by AlphaScreen.
The maximum concentration in the assay was 100 µM and compounds showing less than 50% inhibition at this concentration are labeled >100 µM.