Table I.
List of anti-apoptotic genes upregulated in B cells from B6.Sle1b mice
| Gene name | Fold change | P value |
|---|---|---|
| BCL2L1 | 2.2 | 0.03 |
| SPHK1 | 2.2 | 0.007 |
| HMGB2 | 2.5 | 0.048 |
| BIRC5 | 2.6 | 0.011 |
| RRM2 | 1.9 | 0.018 |
| METAP2 | 1.6 | 0.031 |
Tabulated anti-apoptotic genes were significantly upregulated in sorted B cells derived from 3 mo old B6.Sle1b mice as determined by Illumina Bead Chip arrays (Mouse WG-6 V2). Gene expression is shown in terms of increased fold change in B6.Sle1b mice compared to B6 controls. Statistical analysis was performed by pairwise homogeneous t-test.