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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: J Immunol. 2015 Mar 30;194(9):4555–4566. doi: 10.4049/jimmunol.1402734

Figure 5. SNX17 is involved in TCR and LFA-1 receptor recycling in T cells.

Figure 5

(A, B) Flow cytometric analysis of CD3/CD28 antibody stimulated siControl (black) and siSNX17 (gray) primary human CD4+ T cells treated with 20 μg/ml cycloheximide for 24 hrs and then surfaced labeled for TCRαβ and CD11a. (C) TCRαβ and (D) CD11a recycling was measured in siControl and siSNX17 primary human CD4+ T cells using acid stripping as described in the Materials and Methods. A–D are representative examples of 3 separate experiments. Bars represent mean ± SEM. Horizontal lines indicate statistical comparison between groups, *p≤0.05, **p≤0.0005.