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Virologic, biochemical, and histologic efficacy at week 48 among treated patients with evaluable hepatic hepatitis B virus DNA pairs. 1ALT < 1.25 × upper limit of normal; 2≥ 2-point decrease in Knodell necroinflammatory score with no worsening (≥ 1-point increase from baseline) of Knodell fibrosis score; 3≥ 1-point decrease in Ishak fibrosis score from baseline.
