Table 2.
Correlation between miR-20a and let-7a levels and clinicopathologic features in patients with esophageal squamous cell carcinoma
| Characteristics | n |
Fold change1 |
|
| miR-20a | let-7a | ||
| Gender | |||
| Male | 46 | 1.61 (0.95-2.82) | 0.33 (0.22-0.53) |
| Female | 24 | 1.63 (1.33-2.93) | 0.45 (0.29-0.89) |
| P-value | 0.481 | 0.107 | |
| Age (yr) | |||
| ≤ 60 | 37 | 1.62 (1.24-2.89) | 0.39 (0.23-0.79) |
| > 60 | 33 | 1.62 (1.06-2.82) | 0.35 (0.24-0.64) |
| P-value | 0.463 | 0.900 | |
| Diameter of tumor | |||
| < 4 cm | 36 | 1.51 (0.99-2.47) | 0.40 (0.23-0.79) |
| ≥ 4 cm | 34 | 2.10 (1.33-3.08) | 0.36 (0.24-0.62) |
| P-value | 0.077 | 0.961 | |
| TNM stage | |||
| I/II | 49 | 1.52 (0.95-2.80) | 0.42 (0.28-0.88) |
| III/IV | 21 | 2.04 (1.40-3.40) | 0.24 (0.19-0.39) |
| P-value | 0.118 | 0.009 | |
| Distant metastasis | |||
| M0 | 61 | 1.62 (1.10-2.82) | 0.39 (0.24-0.79) |
| M1 | 9 | 1.64 (1.21-4.45) | 0.35 (0.12-0.44) |
| P-value | 0.300 | 0.174 | |
| Histologic grade | |||
| Well differentiated | 25 | 1.50 (1.10-2.41) | 0.45 (0.25-0.59) |
| Moderately differentiated | 28 | 1.76 (1.04-2.82) | 0.33 (0.26-0.97) |
| Poorly differentiated | 17 | 1.75 (1.21-3.29) | 0.30 (0.22-0.62) |
| P-value | 0.632 | 0.849 | |
1
Median of relative expression with 25th-75th percentile; Mann-Whitney U test waws performed for comparisons between two groups and Kruskall-Wallis test for comparisons among three groups.