Table 2.
Top 10 canonical pathways altered by both asbestos and silica in NHBE (24 h)
| Rank | Canonical pathway |
|---|---|
| 1 | Granulocyte adhesion and diapedesis |
| 2 | Agranulocyte adhesion and diapedesis |
| 3 | Glucocorticoid receptor signaling |
| 4 | TNFR2 signaling |
| 5 | Role of macrophages, fibroblasts and endothelial cells in rheumatoid arthritis |
| 6 | IL-6 signaling |
| 7 | Aldosterone signaling in epithelial cells |
| 8 | PPAR signaling |
| 9 | IL-17A Signaling in gastric cells |
| 10 | IL-10 Signaling |
Top 10 canonical pathways significantly enriched by alteration in gene expression by both asbestos and silica as determined by core analysis of commonly altered gene changes in IPA.