Table 2.
Clinical Characteristics and Outcomes
| Characteristic | Community-Onset Diarrhea (n = 422) |
Hospital-Onset Diarrhea (n = 112) |
P Value | ||
|---|---|---|---|---|---|
| Admission length of stay, days, median (IQR) | 3.17 | 1.91–5.50 | 17.7 | 7.63–28.4 | <.005 |
| Course | .835 | ||||
| Self-limited | 386 | 91.50 | 102 | 91.10 | |
| Continued diarrhea | 31 | 7.35 | 8 | 7.14 | |
| Bowel resection | 5 | 1.18 | 2 | 1.79 | |
| Mortality during admission | 4 | 0.95 | 10 | 8.93 | <.005 |
| Readmission with acute diarrhea | .397 | ||||
| Within 30 days | 43 | 59.70 | 16 | 69.60 | |
| Within 30–90 days | 29 | 40.30 | 7 | 30.40 | |
| MPA and MMF usage on admission (n = 405) | <.005 | ||||
| MPA | 185 | 57.90 | 12 | 14.10 | |
| MMF | 135 | 42.20 | 73 | 85.90 | |
| MMF management | .861 | ||||
| No change | 85 | 63.00 | 46 | 63.00 | |
| Decrease | 24 | 17.78 | 13 | 17.81 | |
| Change to MPA | 7 | 5.19 | 4 | 5.48 | |
| Increase | 5 | 3.70 | 4 | 5.48 | |
| Change to azathioprine | 1 | 0.74 | 0 | 0.00 | |
| Discontinued | 13 | 9.63 | 5 | 6.85 | |
| Added | 0 | 0.00 | 1 | 1.37 | |
| MPA management | .008 | ||||
| No change | 126 | 67.38 | 6 | 46.15 | |
| Decrease | 37 | 19.79 | 2 | 15.38 | |
| Change to MMF | 0 | 0.00 | 0 | 0.00 | |
| Increase | 1 | 0.53 | 2 | 15.38 | |
| Change to azathioprine | 0 | 0.00 | 0 | 0.00 | |
| Discontinued | 23 | 12.30 | 3 | 23.08 | |
Data are presented as No. (%) unless otherwise specified.
Abbreviations: IQR, interquartile range; MMF, mycophenolate mofetil; MPA, mycophenolic acid.