Table 3.

Adjusted hazard ratios for sodium quartiles with mortality outcomes, using quartile IV as reference

Mortality outcome	Hazard ratio (95% CI)	P value
All-cause mortalitya(n = 3,052)
QI	0.81 (0.66–1.00)	0.05
QII	0.90 (0.73–1.10)	0.31
QIII	0.88 (0.71–1.09)	0.23
All cardiovascular mortalityb
QI	1.00 (0.71–1.42)	0.99
QII	0.96 (0.68–1.36)	0.82
QIII	1.06 (0.75–1.49)	0.74
Limited cardiovascular mortalityc
QI	0.93 (0.63–1.39)	0.73
QII	0.82 (0.55–1.22)	0.34
QIII	1.06 (0.73–1.55)	0.74
Noncardiovascular mortalityd
QI	0.57 (0.41–0.80)	0.001
QII	0.85 (0.63–1.16)	0.31
QIII	0.80 (0.59–1.10)	0.18

All covariables listed are those at baseline. Backwards elimination approach was used to arrive at all final models.

Abbreviations: QI, quartile I; QII, quartile II; QIII, quartile III.

^aAdjusted for age, sex, race, body mass index (BMI), systolic blood pressure (SBP), estimated glomerular filtration rate (eGFR), urine potassium, hematocrit, HxDM, Hx smoking, history of baseline left ventricular hypertrophy (Hx baseline LVH).

^bAdjusted for age, sex, race, BMI, SBP, eGFR, urine potassium, hematocrit, plasma renin activity, HxDM, Hx smoking, history of baseline left ventricular hypertrophy.

^cAdjusted for age, sex, race, BMI, SBP, urine creatinine, plasma renin activity, HxDM, Hx smoking, history of baseline left ventricular hypertrophy.

^dAdjusted for age, sex, race, BMI, SBP, hematocrit, urine potassium, HxDM, Hx smoking. Abbreviations: Hx smoking, history of smoking; HxDM, history of diabetes.