Figure 3.

miR-367 expression correlated with the prognosis of PDAC. (A) Kaplan–Meier survival analysis of PDAC patients grouped by the expression levels of miR-367. The expression levels of mature miR-367 were evaluated by TaqMan real-time qPCR, and the median value of all 65 cases was defined as the cutoff value classified 65 tumour cases into low expression (n=33) and high expression of miR-367 (n=32). (B) The correlation between the expressions of Smad7 and miR-367 was assessed in 65 PDAC patients. Smad7 protein expression was evaluated by immunohistochemistry (Wang et al, 2009b). Statistical analysis of the difference in miR-367 levels between Smad7(−) and Smad7(+) samples was conducted using ANOVA test.