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Effects of chronic pretreatment with MAK (1 g/kg) on the expression of necroptotic factor gene expression after H/I. Expression levels of RIP1 (a) and RIP3 (b) mRNA at 6 (after 6 h) or 24 h (after 24 h) of reoxygenation after H/I in the penumbral cortex from the mice in each group, determined by real-time RT-PCR analysis.; n = 6–10 in each group. ∗∗, ∗∗∗ P < 0.01, 0.001. †† P < 0.01 compared with the H/I-treated control group.
