Table 3.
Distribution of the genotypes and alleles of the rs7833904 polymorphism in the male subgroups of coronary artery disease (CAD) patients and controls.
Genotype/allele | CAD N = 138 |
Control N = 156 |
Model | OR (CI 95%), P |
---|---|---|---|---|
n (%) | n (%) | |||
TT | 29 (21.02%) | 57 (36.54%) | Additive | 1 |
AT | 66 (47.82%) | 71 (45.51%) | 1.82 (1.04–3.19), 0.047* | |
AA | 43 (31.16%) | 28 (17.95%) | 3.01 (1.57–5.79), 0.001* | |
AA + AT TT |
109 (78.98%) 29 (21.02%) |
99 (63.46%) 57 (36.54%) |
Dominant | 2.16 (1.28–3.65), 0.005*
1 |
AT + TT AA |
95 (68.84%) 43 (31.16%) |
128 (82.05%) 28 (17.95%) |
Recessive | 0.48 (0.28–0.83), 0.012*
1 |
| ||||
A | 152 (55.07%) | 127 (40.70%) | 1.79 (1.28–2.48), 0.0006∗ vs T | |
T | 124 (44.93%) | 185 (59.3%) | 0.56 (0.40–0.77), 0.0006∗ vs A |
* P < 0.05—statistically significant differences between groups.