Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 8;43(7):e44. doi: 10.1093/nar/gku1393

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — A schematic representation of OncoIMPACT's algorithmic framework. (a) Overview of OncoIMPACT's workflow involving three main stages of data-processing. (b) Depiction of OncoIMPACT's search through a multi-dimensional space to set network and expression parameters (F, fold change of genes; L, length of path; D, degree of nodes). (c) Parsimony-based matching of potential driver and phenotype genes in a bipartite graph to eliminate back-seat drivers. Solid and dashed lines indicate the association of potential driver genes to phenotype genes that were accepted and rejected, respectively.