Table 1. Gene- and exon-level alterations of high-confidence interaction partners of U2AF35 in ab- cells.
| Partner gene | Gene-levela | Exon-level |
|---|---|---|
| U2AF2 | −1.17 | NS |
| SRSF1 | −0.43 | Longer 3′UTR as a result of promotion of distal APA |
| SF3B3 | 0.54 | Longer 3′UTR as a result of promotion of distal APA |
| SF3B14 | −0.65 | NS |
| SF3B1 | NS | Promotion of distal APA, retention of intron containing proximal APA |
| CDC5L | −0.71 | NS |
| PLRG1 | NS | Longer 3′UTR as a result of promotion of distal APA |
| ZCCHC8 | −0.51 | NS |
| U2AF26 | 1.43 | NS |
| SNRPA1 | 0.97 | NS |
| SAP18 | −0.53 | NS |
| SON | −0.58 | Promotion of putative proximal APA site |
| MCM5 | −0.55 | NS |
| NHP2L1 | −0.47 | Promotion of proximal alternative transcription initiation site |
aNegative log2-fold values indicate upregulation in ab- cells; positive values indicate downregulation. NS, not significantly altered by U2AF35 depletion.