Skip to main content
. 2015 May 1;38(5):777–785. doi: 10.5665/sleep.4674

Figure 3.

Figure 3

Sleep deprivation increases seizure activity following RNAi knockdown of sesB. During baseline, seizure activity of RNAi lines elav;UASDcr2/+ > sesBRNAi#1/+ and elav;UAS-Dcr2/+ > sesBRNAi#2/+ exhibited increased seizure activity compared to their parental controls (elav;UAS-Dcr2/+, sesBRNAi#1/+, and sesBRNAi#2/+); seizure activity was further increased in elav;UAS-Dcr2/+ > sesBRNAi#1/+ and elav;UAS-Dcr2/+ > sesBRNAi#2/+ following sleep deprivation (n = 16–20 flies/condition). *P < 0.05 modified Bonferroni test. Although not indicated on the graph, the seizure duration of elav;UASDcr2/+ > sesBRNAi#2/+ was also statistically different from the elav;UAS-Dcr2/+ parental control.