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Valproic Acid (VPA) reduces sleep deprivation induced seizure activity in sesb9Ed-4/+ flies. Vehicle-fed sesb9Ed-4/+ flies show a significant increase in seizure activity following sleep deprivation compared to untreated siblings. In contrast, seizure activity was not increased following sleep deprivation in sesb9Ed-4/+ flies maintained on 25 mM VPA compared to their untreated, VPA-fed siblings; *P < 0.05 modified Bonferroni test.
