Table 1. Comparison of paw withdrawal threshold among the OA group, vehicle group, and normal control group (n = 8, mean ± SD, g).
| Groups | Before injection | Day 3 | Day 7 | Day 14 | Day 28 | Day 42 | Day 56 |
|---|---|---|---|---|---|---|---|
| OA | 17.75 ± 5.09 | 7.25 ± 1.83* | 7.75 ± 1.69* | 5.75 ± 1.67* | 10.50 ± 2.93 | 13.13 ± 2.59 | 13.75 ± 2.32 |
| Vehicle | 19.13 ± 5.69 | 11.63 ± 2.88 | 16.88 ± 6.13 | 16.38 ± 3.89 | 15.13 ± 4.94 | 17.13 ± 5.74 | 17.75 ± 5.09 |
| Normal control | 18.50 ± 6.44 | 20.5 ± 5.88 | 18.63 ± 6.99 | 17.13 ± 5.74 | 19.13 ± 5.69 | 19.88 ± 6.75 | 17.88 ± 7.04 |
*, vs the vehicle group and normal control group, P < 0.05