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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: J Invest Dermatol. 2015 May;135(5):1221–1224. doi: 10.1038/jid.2015.4

Figure 1. Clinical and microscopic images of Merkel cell carcinoma.

Figure 1

a) Representative MCC on the left hand of a 70-year-old man. Microscopic images with magnified insets of a primary MCC tumor with b) Hematoxylin and eosin stain showing salt and pepper chromatin pattern, frequent mitotic figures and nuclear molding characteristic of MCC; c) MCPyV Large T-Ag immunohistochemistry (CM2B4 antibody) shows viral protein expression in tumor cells but not adjacent stroma; d) Cytokeratin 20 (CK20) immunohistochemistry demonstrates characteristic dot-like peri-nuclear staining. Scale bar, 50 μM