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. Author manuscript; available in PMC: 2015 May 13.
Published in final edited form as: Nature. 2014 Oct 29;515(7526):209–215. doi: 10.1038/nature13772

Extended Data Figure 7. De novo variants in SET lysine methyltransferases and JmjC lysine demethylases.

Extended Data Figure 7

Mis3 are in black, LoF in red, and variants identified in other disorders in grey (Fig. 5). JmjC, Jumonji C domain; JmjN, Jumonji N domain; JmjC, PHD, plant homeodomain; ARID, AT-rich interacting domain; SET, Su(var)3-9, Enhancer-of-zeste, Trithorax domain; FYR N, FY-rich N-terminal domain; FYR C, FY-rich C-terminal domain; PWWP, Pro-Trp-Trp-Pro domain; HMG, high mobility group box; AWS, associated with SET domain; Bromo, bromodomain; BAH, bromo adjacent homology.