Figure 2.
Changes in serum biochemistry and proinflammatory cytokine levels in the BDL rats-treated with oleanolic acid. The SD rats were pre-treated with oral administration of oleanolic acid at 100 mg/kg for 1 day, underwent BDL surgery, and continued to be treated with oleanolic acid daily for 3, 7, or 14 days. A. Serum levels of ALT, AST, and ALP. B. Serum levels of proinflammatory cytokines TNF-α, IL-1β, and IL-6. Data are expressed as mean ± SD (n = 7 rats per group). *P < 0.05 vs the sham operated normal rats-treated with saline, #P < 0.05 vs the BDL model rats treated with saline.