Table 2.
Comparison of long term i-PTH level and bone metabolism change between LCD and SCD patients after 1-2 yr PD
| study | Serum I-PTH | Bone Metabolism |
|---|---|---|
| Kang (2012) | SCD = 145.2 ± 155.4 (ng/l) | The adjusted 2 yr decrement of BMC, L-spine BMD, subtotal BMD and total BMD from base line was greater in the LCD group than in the SCD group |
| LCD = 213.2 ± 147.7 (ng/l) | ||
| At 2 yr; P = 0.008 | ||
| Sanchez (2004) | ΔPTH (SCD) = 21.3 ± 88.1 (pg/ml) | The rise in dynamic parameters (mineral apposition rate and bone formation rate) in LCD patients almost reached statistical significance (P = 0.07) |
| ΔPTH (LCD) = 174.4 ± 254.2 (pg/ml) at 1 yr; P < 0.05 | ||
| Weinreich (1996) | SCD = 7.5 (1-100) (pmol/l) | No difference was observed in radiological findings between LCD and SCD patients at 2 yr after PD |
| LCD = 17 (1-175) (pmol/l) at 2 yr; P < 0.05 | ||
| Johnson (1996) | At the 3-month and 6-month intervals, mean PTH levels were significantly higher in the LCD patients compared with SCD patients (P = 0.004 and 0.016 respectively). No significant differences were detected between the two groups in the last six months of the study. | Z-scores for total and regional BMDs did not differ between LCD and SCD group at 1 yr. |
SCD = standard calcium lysate; LCD = low calcium lysate; PTH = parathyroid hormone; BMC = bone mineral content; BMD = bone mineral density; PD = peritoneal dialysis.