Table 3.
Comparisons | OR | 95% CI | P value | Heterogeneity | Effects model | |
---|---|---|---|---|---|---|
| ||||||
I2 | P value | |||||
B vs A | ||||||
rs9642880 | 1.20 | 1.13–1.27 | < 0.00001 | 0% | 0.53 | F |
Caucasian | 1.18 | 1.09-1.28 | < 0.0001 | 0% | 0.63 | F |
Asian | 1.22 | 1.11-1.35 | < 0.0001 | 25% | 0.26 | F |
rs2294008 | 1.14 | 1.11-1.18 | < 0.00001 | 14% | 0.32 | F |
Caucasian | 1.13 | 1.09-1.17 | < 0.00001 | 69% | 0.07 | F |
Asian | 1.22 | 1.11-1.35 | < 0.0001 | 0% | 0.99 | F |
BB vs AA | ||||||
rs9642880 | 1.37 | 1.21–1.55 | < 0.00001 | 0% | 0.54 | F |
Caucasian | 1.39 | 1.19-1.62 | < 0.0001 | 0% | 0.71 | F |
Asian | 1.33 | 1.07-1.65 | 0.009 | 33% | 0.21 | F |
rs2294008 | 1.28 | 1.20-1.37 | < 0.00001 | 0% | 0.57 | F |
Caucasian | 1.28 | 1.19-1.37 | < 0.00001 | 61% | 0.11 | F |
Asian | 1.32 | 1.03-1.69 | 0.03 | 0% | 0.86 | F |
AB vs AA | ||||||
rs9642880 | 1.20 | 1.09–1.32 | 0.0002 | 6% | 0.39 | F |
Caucasian | 1.07 | 0.94-1.23 | 0.30 | 0% | 0.97 | F |
Asian | 1.36 | 1.18-1.54 | < 0.0001 | 0% | 0.68 | F |
rs2294008 | 1.23 | 1.17-1.30 | < 0.00001 | 0% | 0.65 | F |
Caucasian | 1.21 | 1.14-1.29 | < 0.00001 | 0% | 0.53 | F |
Asian | 1.32 | 1.16-1.51 | < 0.0001 | 0% | 0.74 | F |
AB + BB vs AA | ||||||
rs9642880 | 1.25 | 1.14–1.37 | < 0.00001 | 0% | 0.56 | F |
Caucasian | 1.17 | 1.03-1.33 | 0.01 | 0% | 0.90 | F |
Asian | 1.35 | 1.18-1.54 | < 0.00001 | 0% | 0.41 | F |
rs2294008 | 1.25 | 1.19-1.31 | < 0.00001 | 0% | 0.64 | F |
Caucasian | 1.23 | 1.17-1.30 | < 0.00001 | 13% | 0.28 | F |
Asian | 1.32 | 1.17-1.50 | < 0.0001 | 0% | 0.86 | F |
BB vs AA + AB | ||||||
rs9642880 | 1.26 | 1.13-1.40 | < 0.0001 | 0% | 0.54 | F |
Caucasian | 1.33 | 1.17-1.51 | < 0.0001 | 0% | 0.63 | F |
Asian | 1.09 | 0.89-1.34 | 0.40 | 0% | 0.63 | F |
rs2294008 | 1.13 | 1.07-1.20 | < 0.0001 | 0% | 0.56 | F |
Caucasian | 1.13 | 1.06-1.20 | < 0.0001 | 57% | 0.13 | F |
Asian | 1.17 | 0.92-1.48 | 0.20 | 0% | 0.76 | F |
A represents the major allele, B represents the minor allele, F: fixed effects model, R: random effects model.