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. 2015 Feb 15;8(2):3063–3071.

Figure 2.

Figure 2

ITGB8 silencing increases accumulation Rhodamine-123 accumulation, cell cycle arrest and apoptosis rate. A and B: Rhodamin-123 accumulation assay was performed on HepG2 cells (Parent), HepG2/G cells (Control) and HepG2/G cells infected with shRNA-1 (shRNA-1) or shRNA-2 (shRNA-2). The data are shown as the means ± SD (n = 3). C and D: HepG2 cells (Parent), HepG2/G cells (Control) and HepG2/G cells infected with shRNA-1 (shRNA-1) or shRNA-2 (shRNA-2) was treated with gefitinib for 24 hours, then Cell cycle phase was analyzed by flow cytometry. The data are shown as the means ± SD (n = 3). E and F: HepG2 cells (Parent), HepG2/G cells (Control) and HepG2/G cells infected with shRNA-1 (shRNA-1) or shRNA-2 (shRNA-2) was treated with gefitinib for 24 hours, then apoptosis rate was determined. The data are shown as the means ± SD. *P < 0.05, **P < 0.01.