Table 2.

Summary of the functions of CD98 mentioned in this review

Function	CD98 domain involved	Reference
Amino acid transport-associated functions
Interact with amino acid transporters and support amino acid transport	Extracellular domain	[61–65]
Integrin signaling-associated functions
Regulate cell homeostasis: cell growth, proliferation, migration, adhesion development	Cytoplasmic and transmembrane domains	[11, 14, 20, 43, 44, 61, 68–77, 81, 82, 86, 87]
Regulate immune responses		[11–13, 90–96]