Table I. Summary of Cancer/Testis Antigen Expression in Prostate Cells.
| Gene name | Chromosome | Fold change average (LNCaP) | Fold change average (PC-3) | MAGEA subcluster |
|---|---|---|---|---|
| MAGEA2B | Xq28 | 844 | ND | III |
| GAGE7 | Xp11.2 | 745 | ND | |
| MAGEA3 | Xq28 | 154 | ND | III |
| MAGEA1 | Xq28 | 105 | ND | IV |
| MAGEA4 | Xq28 | 94.9 | ND | II |
| CSAG2 | Xq28 | 86.4 | ND | III |
| MAGEA12 | Xq28 | 84.4 | ND | III |
| MAGEA6 | Xq28 | 38.2 | ND | III |
| CTAG1A | Xq28 | 31.2 | ND | |
| XAGE1 | Xp11.22 | 26 | ND | |
| GAGE4 | Xp11.4 | 16.5 | ND | |
| FMR1NB | Xq27.3-q28 | 13.8 | ND | |
| DDX43 | 6q12-q13 | 11.8 | ND | |
| GAGE3 | Xp11.4p11.2 | 7.86 | ND | |
| SSX6 | Xp11.2 | 5.63 | ND | |
| SSX7 | Xp11.23 | 4.52 | ND | |
| CSAG1 | Xq28 | 3.71 | ND | III |
| MAGEA8 | Xq28 | 3.57 | ND | I |
| MAGEA5 | Xq28 | 2.93 | ND | II |
| FTHL17 | Xp21 | ND | 3.97 |
RNA samples from normal prostate epithelial cells (PrEC), LNCaP and PC-3 cells were profiled for CTA expression using the CT Array v2.0 as described in the Experimental Procedures. The average of two independent experiments is shown. Roman numbers indicate the number of the MAGE-A subcluster. ND, expression was not detectable in the microarray experiment.