Stage-dependent benefits and risks of pimobendan in mice with genetic dilated cardiomyopathy and progressive heart failure

. 2015 Mar 17;172(9):2369–2382. doi: 10.1111/bph.13062

TARGETS
Transporters^a
NCX1, sodium-calcium exchanger (SLC8A1),
Enzymes^b
CaMKII, calmodulin-dependent kinase II
PDE3, phosphodiesterase 3
PKA, protein kinase A
SERCA2a
Ion channels^c
L-type Ca2+ channel, Cav1.x channels
RyR2, ryanodine receptor 2