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Molecular model of BK and β1 interaction. (A) The illustration shows the α-subunit of the BK channel with the voltage-sensor domain in green and the pore domain in violet. RCK domains in the C terminus of BK are also shown. (B) The amino terminus of the β1-subunit (blue) is involved in the modulation of gating through the intracellular N terminus, specifically by K3K4 residues, shown as yellow balls.
