Table 2.
Effects of Intervention by Randomized Group on Patient-Reported Outcomes at 12-Month Follow-up
| Mean (SD) |
Group difference in mean change (95% CI), p-value |
||||
|---|---|---|---|---|---|
| Outcome | Baseline | 12-mo follow-up | Change | Unadjusted | Adjusted* |
| SPADI total, % | |||||
| TP | 29.8 (22.4) | 20.6 (26.2) | −9.2 (18.0) | −1.4 (−14.4 to 11.6), 0.82 | −5.7 (−18.1 to 6.6), 0.35 |
| PRET | 21.1 (18.3) | 10.5 (13.4) | −10.6 (20.8) | ||
| NDII, % | |||||
| TP | 51.8 (23.1) | 69.1 (28.6) | +17.2 (16.6) | +0.1 (−12.1 to 12.3), 0.98 | +2.4 (−10.3 to 15.0), 0.70 |
| PRET | 60.0 (21.3) | 77.4 (17.1) | +17.3 (20.0) | ||
| FACT-An + FACT-G, 0–188 | |||||
| TP | 139.4 (25.7) | 144.4 (30.7) | +5.0 (14.9) | +3.4 (−11.9 to 18.8), 0.65 | +3.5 (−14.1 to 21.1), 0.69 |
| PRET | 137.4 (24.3) | 145.9 (24.4) | +8.4 (29.3) | ||
| FACT-G, 0–108 | |||||
| TP | 80.9 (16.1) | 82.2 (14.9) | +1.3 (8.7) | +1.8 (−6.1 to 9.8), 0.64 | +1.4 (−6.3 to 9.2), 0.72 |
| PRET | 80.6 (15.2) | 83.7 (12.0) | +3.1 (14.7) | ||
| FACT-Fatigue, 0–52 | |||||
| TP | 36.1 (8.8) | 39.3 (11.3) | 3.2 (7.3) | +1.56 (−5.1 to 8.2), 0.64 | +1.0 (−6.6 to 8.6), 0.79 |
| PRET | 35.0 (8.3) | 39.7 (10.0) | 4.7 (12.1) | ||
*
Adjusted for baseline value, age, gender, cancer stage, time since surgery, neck dissection type, and pain medication use.
SPADI=Shoulder Pain and Disability Index; TP=standard therapeutic protocol; PRET=progressive resistance exercise training; NDII=Neck Dissection Impairment Index; FACT-G=Functional Assessment of Cancer Therapy – General Scale; FACT-An=Functional Assessment of Cancer Therapy Anemia Scale; FACT-Fatigue=Functional Assessment of Cancer Therapy Fatigue subscale.