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. 2015 Apr 10;6:6789. doi: 10.1038/ncomms7789

Figure 8. miR-26a and miR-384-5p are regulated locally in dendrites in LTP.

Figure 8

Cultured hippocampal neurons were transfected with the EGFP construct (for visualization of transfected neurons), treated with TEA (25 mM, 15 min) at 3 days after transfection and fixed at 90 min after stimulation for in situ hybridization. (a) The subcellular distribution of miR-26a and miR-384-5p. (bd) The effect of TEA treatment on dendritic miR-26a and miR-384-5p; representative images are in b, quantification of b is in c and d; n=18–24 neurons for each condition. Data are presented as mean±s.e.m. Mann–Whitney U-test is used for statistical analysis. *P<0.05, ***P<0.001.