FIG 6.

Type I interferons, cytokines, and chemokines released by human monocytes infected with NYVAC-C, NYVAC-C-ΔB19R, and NYVAC-C-ΔB8RB19R. Monocytes from healthy volunteers were infected for 24 h with NYVAC-C, NYVAC-ΔB19R, or NYVAC-CΔB8RB19R, and the concentrations of IFN-α, IFN-β, CXCL10/IP-10, TNF, IL-1β, and IL-6 were measured in cell culture supernatants. Box plots of three separate experiments including a total of eight subjects are shown. Data points are means for duplicate or triplicate samples per subject. Bottom, median, and top lines, 25th, 50th, and 75th percentiles, respectively; vertical lines with whiskers, the range of values.