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. 2015 Jan 21;89(7):3888–3909. doi: 10.1128/JVI.03597-14

FIG 5.

FIG 5

Structure of the MneRV2 genomic region homologous to KSHV ORF50/K8/K8.1. (A) Graphical representation of the genomic structure of MneRV2 from bp 65000 to 71000 containing the MneRV2 homologs of the KSHV ORFs 50, K8, and K8.1. The positions of the TATA promoter (P) motifs of KSHV ORF50 (TTTAAAAA), K8 (TATAAA), and K8.1 (AATATTAA) conserved in MneRV2 and RRV are indicated. The polyadenylation (pA) site downstream of the K8.1 homologs, which is conserved between KSHV, MneRV2, and RRV, is shown in black, while the polyadenylation site downstream of the MneRV2 and RRV homologs of K8, which is not conserved in KSHV, is shown in red. (B) Graphical representations of the potential spliced transcripts from this region in MneRV2 are shown based on homology to KSHV and RRV (see the text) and the presence of conserved splice donor and acceptor sites. The putative encoded ORFs and their sizes are shown.