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. 2015 Feb 18;89(9):5083–5096. doi: 10.1128/JVI.00213-15

TABLE 2.

Key characteristics of the E1B-55K mutant viruses used in this study

Virus E1B-55K mutation(s) Likely defect Reference(s) or source
dl110 Deletion, frameshift Null 42
dl1520 Stop codon, deletion Null 39
dl338 Deletion Null 41
4149 4 stop codons Null for all 55K related 104
4100 None None 43
4108 T255A E4orf6 binding Identical mutation to virus described in reference 60
4109 H260A p53 binding, E4orf6 binding Identical mutation to virus described in reference 60
4127 C454S C456S Mre11 binding 105
4174 S490A S491A T495A Non-phospho C terminus 10, 106, 107
4185 P70T S73A Unknown (P70T S73A) 108
4197 E472A Daax interaction 1 55
4198 K185A K187A Daax interaction 2 55
4216 GVVI233–236AAAS SUMO interaction Not published
4217 V339A V341A I342S SUMO interaction Not published
4227 S490D S491D T494D Phosphomimetic C terminus 57, 107