TABLE 2.
Levels of anti-CLDN1 MAbs in sera of human liver-chimeric mice in in vivo HCV infection experiments
| Mouse no. | Antibody level in serum (μg/ml)a |
|
|---|---|---|
| Day 3 | Day 10 | |
| 3A2-1 | 1.67 ± 0.10 | <0.085 |
| 3A2-2 | 1.13 ± 0.01 | <0.085 |
| 3A2-3 | 0.15 ± 0.07 | <0.085 |
| 3A2-4 | 1.85 ± 0.23 | <0.085 |
| 7A5-1 | 282.6 ± 20.9 | 110.3 ± 8.3 |
| 7A5-2 | 224.7 ± 8.7 | 95.7 ± 5.9 |
| 7A5-3 | <0.21 | 14.0 ± 0.3 |
| 7A5-4 | 105.3 ± 3.4 | 12.6 ± 0.3 |
a
Data represent the means ± SD (n = 4). The limit of detection was 0.085 for the 3A2-treated mice and 0.21 for the 7A5-treated mice.