TABLE 1.
Vif polymorphisms associated with patient phenotype (EC versus non-EC)a
| Amino acid residue | No. (%) of EC with indicated polymorphism | No. (%) of EC without indicated polymorphism | No. (%) of non-EC with indicated polymorphism | No. (%) of non-EC without indicated polymorphism | P value | q value | Subtype B consensus |
|---|---|---|---|---|---|---|---|
| 030H | 1 (2) | 45 (98) | 20 (22) | 70 (75) | 0.0019 | 0.21 | Y |
| 030Y | 45 (98) | 1 (2) | 69 (74) | 21 (23) | 0.0010 | 0.21 | Y |
| 039F | 28 (61) | 18 (39) | 30 (32) | 60 (65) | 0.0032 | 0.24 | F |
| 047T | 40 (87) | 6 (13) | 54 (58) | 36 (39) | 0.0015 | 0.21 | T |
| 159I | 32 (70) | 14 (30) | 29 (31) | 61 (66) | <0.0001 | 0.0045 | I |
| 159R | 4 (9) | 42 (91) | 29 (31) | 61 (66) | 0.0027 | 0.24 | I |
a
All polymorphisms, regardless of their observed frequency in our data set, were analyzed. Polymorphisms with a P value of <0.05 and q value of <0.4 are reported. EC, elite controller.