Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 9;9:2001–2027. doi: 10.2147/DDDT.S77071

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Zhang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Sch B induces cell cycle arrest in mouse AML-12 and RAW 264.7 cells in a time-dependent manner.

Notes: Cells were treated with Sch B at 25 μM for 6, 24, 48, and 72 hours and then subjected to flow cytometric analysis. The PI-stained DNA fluorescence intensity is shown in histogram overlay for cell cycle distribution over 72 hours in mouse AML-12 and RAW 264.7 cells (A). The flow cytometer collected 20,000 events for analysis. The bar graphs show the percentage of AML-12 and RAW 264.7 cells in G₁, S, and G₂/M phases (B). Data are the mean ± SEM of three independent experiments. *P<0.05; **P<0.01; and ***P<0.001 by one-way ANOVA.

Abbreviations: Sch B, schisandrin B; SEM, standard error of the mean; ANOVA, analysis of variance; PI, propidium iodide.