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. 2015 Apr 9;9:2001–2027. doi: 10.2147/DDDT.S77071

Figure 5.

Figure 5

Figure 5

Sch B concentration-dependently induces apoptotic cell death in mouse AML-12 and RAW 264.7 cells.

Notes: Flow cytometric dot plots of specific cell populations (live, early apoptosis, and late apoptosis) in mouse AML-12 and RAW 264.7 cells treated with Sch B at 0.1, 1, 10, and 25 μM for 24 hours (A). Bar graphs showing the percentage of apoptotic cells in AML-12 and RAW 264.7 cells treated with Sch B at 0.1, 1, 10, and 25 μM for 24 hours (B). Data are the mean ± SEM of three independent experiments. *P<0.05 and **P<0.01 by one-way ANOVA.

Abbreviations: Sch B, schisandrin B; SEM, standard error of the mean; ANOVA, analysis of variance; DMSO, dimethyl sulfoxide; PE, phycoerythrin; 7-AAD, 7-aminoactinomycin D; QI, debris.