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. Author manuscript; available in PMC: 2015 Apr 20.
Published in final edited form as: Cell Rep. 2014 Sep 18;8(6):2031–2043. doi: 10.1016/j.celrep.2014.08.038

Figure 6. Inferred Regulatory Edges for Transcriptional Complexes.

Figure 6

(A) Transcriptional regulatory motifs, representing instances where an interacting protein regulates its binding partner (1:1), combinatorial regulation of a target by two interacting factors (2:1), and regulation of interacting proteins by a single factor (1:2). Red edges indicate protein-protein interactions while grey edges with arrows indicate directional regulatory edges. (B) The components of the Drosophila dREAM complex recovered in our interaction network. (C) Transcriptional regulators of Dp-E2f (D) Basal Transcription Machinery components (E) Cell Cycle Proteins (F) DNA Replication Related Proteins (G) Transcription (H) Chromatin Related (I) Unannotated targets of Dp/E2f.