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. 2015 Apr 11;15:266. doi: 10.1186/s12885-015-1251-8

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© Pasiliao et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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IMP3 regulates CD44 and KIF11. (A) Total CD44 protein was measured in whole cell lysates 48 h after transfection. Treatment with IMP3 siRNA resulted in a significant decrease in CD44 protein relative to scrambled siRNA-treated controls. Inset Representative blots of CD44 and corresponding β-actin. *P < 0.05 relative to scrambled siRNA-transfected controls. (B) Levels of KIF11 and KIF14 mRNA were measured 48 h after siRNA transfection and expressed in amount of fold-change relative to scrambled siRNA-treated controls. *P < 0.05 relative to scrambled siRNA-transfected controls.