Table 4.
The DI/SPF and DNA heteroploid changes of 113 follow-up cases
| HPV infection (N)
|
DI
|
P | SPF
|
P | DNA heteroploid
|
P | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Before follow-up | After follow-up | Before follow-up | After follow-up | Before follow-up | After follow-up | Before follow-up | After follow-up | ||||
| Non-high-risk HPV | 11 | 0 | 1.003±0.060 | 1.001±0.035 | 0.810 | 4.463±0.417 | 4.264±0.229 | 0.069 | 1/11 (9.1%) | 0 | 0.306 |
| Single high-risk HPV | 45 | 6 | 1.070±0.098 | 1.032±0.060 | <0.001* | 5.055±1.119 | 4.387±0.566 | <0.001* | 17/45 (37.8%) | 3/45 (6.7%) | <0.001* |
| Multiple high-risk HPV | 57 | 11 | 1.111±0.088 | 1.066±0.071 | <0.001* | 6.487±3.024 | 5.711±2.172 | 0.043* | 29/57 (50.9%) | 15/57 (26.3%) | 0.007* |
Note:
*
It has statistical difference (P<0.05) before and after follow-up.
Abbreviations: DI, DNA index; HPV, human papillomavirus; SPF, S-phase cells’ peak percentage.