Table 2.
Concordance Between Plasma RNA and pvDNA Coreceptor Tropism
| Test Method | Reference Method | non-R5 (%) Test Ref. | Concord. (%) | Sens. (%) 1 | Spec. (%) 2 | Kappa 3 | |
|---|---|---|---|---|---|---|---|
| pvDNA (T1) |
Plasma RNA (T1) |
33% | 24% | 88% | 92% | 86% | 0.70 |
| pvDNA (T2) |
Plasma RNA (T1) |
37% | 24% | 80% | 83% | 78% | 0.53 |
1Sensitivity is defined as concordant non-R5s between the test and reference method/reference method non-R5s.
2Specificity is defined as concordant R5s between the test and reference methods/reference method R5s.
3Kappa: a measure of inter-rater agreement; 0.41-0.60: moderate agreement; 0.61-0.80: good agreement.