Table 2.
Clinico-pathological features of HCC in relation to GEP DNA copy number
| GEP DNA copy number | |||
|---|---|---|---|
| HCC features | No gain | Gain | P 1 |
| Venous infiltration | |||
| Absent | 19 | 7 | 0.397 |
| Present | 29 | 5 | |
| Tumour size | |||
| Small (≤5 cm) | 10 | 3 | 1.000 |
| Large (>5 cm) | 38 | 9 | |
| pTNM stage | |||
| Early stage (I-II) | 31 | 9 | 0.732 |
| Late stage (III-IV) | 17 | 3 | |
| Edmondson grade | |||
| Well differentiation | 41 | 10 | 1.000 |
| Poor differentiation | 7 | 2 | |
| Gender | |||
| Male | 42 | 7 | 0.055 |
| Female | 6 | 5 | |
| Age | |||
| Young (≤60) | 37 | 6 | 0.133 |
| Elderly (>60) | 11 | 6 | |
| Serum AFP level | |||
| Low (≤20 ng/mL) | 21 | 1 | 0.052 |
| High (>20 ng/mL) | 27 | 11 | |
| HBV status (HBsAg) | |||
| Negative | 4 | 5 | 0.015 |
| Positive | 44 | 7 | |
1Pearson chi-square test with Yates continuity correction.
Abbreviations: AFP alpha-fetoprotein, HBV hepatitis B virus, HBsAg hepatitis B surface antigen.