Table 2.

Neutralizing antibody titers (NATs) and survival rates in mice

Group	NATs in pooled serum a of WN-VAX immunized mice (serum dilution)	NATs in serum of of individual mouse b 24 hrs after passive immunization	Survival rate of passively immunized mice c after challenge with WNV NY99
1	2.62d	1.72d	100% (10/10)e
	(1:1)	1.66
		1.73
		1.73
		1.93
2	2.09	1.55	100% (10/10)
	(1:4)	1.36
		1.23
		1.33
		1.27
3	1.65	1.03	100% (10/10)
	(1:16)	<1.00
		<1.00
		<1.00
		<1.00
4	1.01	<1.00	30% (3/10)
	(1:64)	<1.00
		<1.00
		<1.00
		<1.00
Control		Not tested	0% (0/10)

^aused for passive immunization of mice in Groups 1, 2, 3 and 4.

^bOnly 5 mice per experimental group had their serum determined for NATs. These mice were not subjected to virus challenge and were used only for a representative determination of NATs in the group.

^cNATs of their serum were not determined because no blood sampling was done to avoid stressing the animals during virus challenge.

^dNAT log10.

^enumber enclosed in parentheses refer to the number of surviving mice/total no. of mice.