Table 6.
Multivariate regression analyses of death odds for HIV inpatients by age, sex, LOS, and comorbidities
| Independent variables | N ( % dead ) | OR unadjusted | 95% C.I. | OR adjusted | 95% C.I. |
|---|---|---|---|---|---|
| Age groups - years of age | |||||
| 1 - 0 to 17 | 1,057 (2.9) | 1 | 1 | ||
| 2 - 18 to 45 | 40,635 (13.3) | 5.068 | (3.541–7.253) | 4.318 | (2.980–6.257) |
| 3 - 46 to 65 | 12,803 (17.1) | 6.837 | (4.769–9.802) | 5.556 | (3.826–8.069) |
| 4 - 66 and older | 2,544 (22.9) | 9.840 | (6.803–4.232) | 7.955 | (5.424–11.669) |
| Sex | |||||
| Female | 15,210 (11) | 1 | 1 | ||
| Male | 41,834 (15.6) | 1.500 | (1.417–1.589) | 1.407 | (1.326–1.494) |
| LOS median (alive/deceased) | 11.0 / 12.0 | 1.005 | (1.005–1.006) | 1.004 | (1.003–1.005) |
| Elixhauser comorbidity measures | |||||
| No comorbidity* | 16,850 (9.7) | 1 | 1 | ||
| Metastatic cancer | 537 (41.5) | 4.319 | (3.632–5.136) | 3.286 | (2.732–3.952) |
| Weight loss | 3,753 (30.8) | 2.917 | (2.710–3.140) | 2.501 | (2.312–2.704) |
| Fluid and electrolyte disorders | 5,189 (29.9) | 2.897 | (2.715–3.091) | 2.332 | (2.176–2.499) |
| Lymphoma | 1,471 (27.5) | 2.319 | (2.063–2.607) | 2.260 | (2.000–2.553) |
| Pulmonary circulation disorders | 414 (22.9) | 1.782 | (1.416–2.244) | 2.132 | (1.651–2.754) |
| Cardiac arrhythmias | 877 (31.1) | 2.749 | (2.379–3.178) | 2.030 | (1.734–2.375) |
| Solid tumor without metastasis | 2,905 (24.1) | 1.973 | (1.806–2.156) | 1.706 | (1.552–1.876) |
| Coagulopathy | 3,187 (23.8) | 1.953 | (1.794–2.126) | 1.668 | (1.524–1.825) |
| Blood loss and anemia | 1,943 (22.6) | 1.780 | (1.596–1.985) | 1.573 | (1.403–1.764) |
| Peripheral vascular disorders | 230 (23.9) | 1.877 | (1.385–2.544) | 1.416 | (1.025–1.956) |
| Congestive heart failure | 1,029 (22.6) | 1.765 | (1.522–2.046) | 1.403 | (1.195–1.648) |
| Other neurological disorders | 3,329 (20.2) | 1.551 | (1.420–1.694) | 1.364 | (1.242–1.498) |
| Paralysis | 708 (21.6) | 1.654 | (1.380–1.981) | 1.331 | (1.097–1.614) |
| Renal failure | 1,929 (18.9) | 1.403 | (1.248–1.576) | 1.221 | (1.080–1.381) |
| Peptic ulcer disease excluding bleeding | 205 (20.5) | 1.537 | (1.094–2.159) | 1.208 | (0.843–1.733) |
| Alcohol abuse | 4,578 (18.1) | 1.348 | (1.245–1.459) | 1.151 | (1.057–1.253) |
| Liver disease | 13,905 (15.2) | 1.087 | (1.030–1.147) | 1.027 | (0.969–1.088) |
| Hypertension, uncomplicated | 2,191 (12.7) | 0.861 | (0.757–0.978) | 0.685 | (0.597–0.785) |
| Chronic pulmonary disease | 2,458 (11) | 0.726 | (0.638–0.825) | 0.542 | (0.470–0.625) |
| Depression | 1,597 (9.8) | 0.642 | (0.544–0.759) | 0.533 | (0.447–0.635) |
| Nutrient-deficiency anemia | 1,889 (10.7) | 0.706 | (0.609–0.818) | 0.531 | (0.455–0.621) |
| Obesity | 225 (7.1) | 0.455 | (0.273–0.757) | 0.474 | (0.281–0.799) |
*Patients with each comorbidity were compared with patients without that comorbidity. Some Elixhauser comorbidities had no influence on the nonadjusted model and were not included in the analysis, namely rheumatoid arthritis/collagen vascular diseases, psychoses, drug abuse, valvular heart disease, diabetes (both uncomplicated and complicated), complicated hypertension, and hypothyroidism.
LOS = length of hospital stay; OR = odds ratio; 95% CI = 95% confidence interval.